Are men the most manipulable than women?
Not quite sure how this question is supposed to be worded, but it sounds to me like you're asking if men are easier to manipulate and women are. If that is indeed the question you're asking, then the answer is almost universally yes.
There are a lot of men, many of who fancy themselves pickup artists, who will tell you that all you need to do is emotionally stimulate and excite a woman and she'll turn to putty in your in your hands. From there you will be able to easily manipulate her in any fashion you see fit until you tire of her and discard her for someone better. What these delusional idiots fail to realize is that, while they fancy themselves "real man", "alpha males", or "a man among men" these simps are little more than p*ssy whipped and p*ssy addicted losers who feel the only way for them to validate themselves a man is to get into the pants of as many women as they possibly can in the course of their lives. The funny part is, women know this and often times will play along because they understand they're going to get showered with affection, gifts, and fancy dinners. Then, when the dust has settled, the smoke has cleared, and he's dropped her like a bad habit to move on to someone better, she can call all of her friends who will rally around her to throw her a pity party because the last guy she was with turned out to be a degenerate piece of garbage, which in turn strokes her ego. Ironically, chances are good that while she's at this pity party her friends are throwing her, she's gonna meet the guy who will be her next big mistake, get involved with him (pissing away 6 or 7 months of her life in the process), and find herself right back at the center of another pity party when that relationship ends. Lather, rinse, repeat.
To manipulate a woman on the other hand, all you need to do is have enough money that she will be able to live a lifestyle she feels that she is entitled to. The moment she is a relationship with you and determines that you are indeed a man of means, she will begin devising ways to get her hooks into your money and force you out of the picture. Women like this will fight every attempt you make to get them to sign a prenuptial agreement tooth and nail because they know if they do, that would defeat the entire purpose of entering into the relationship with such a man in the first place.
We have Predators, Hunters and Prey, victims.
This is a genetic pattern, not social. We can not avoid the tricks and Games of the Hunters. We can train to recognize early the signals and run away as any wild animal...we are sessile and wait and hope...and get domesticated to follow the cage owner begging for cage care...